VIP
Vasoactive intestinal peptide for neuroprotection and immune research
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Lab-Grade Guarantee
This compound is in independent third-party analysis. Once its Certificate of Analysis is published at /lab-results, the same below-COA-purity reship guarantee applies.
Lab analysis in progress
COA published once HPLC / ESI-MS testing completes
FOR RESEARCH PURPOSES ONLY. This product is strictly for laboratory and research use. Not for human consumption, medical treatment, or any clinical application. By ordering, you confirm you are a qualified researcher or represent a legitimate research institution.
VIP: Key Facts
VIP is a sleep cognitive research peptide supplied by LyzeLabs as a lyophilized reference standard, strictly for laboratory research use. It is available in 1 format starting at $430 per kit. Batch certificates of analysis are published on the lab-results page and matched to the lot number on the vial as verification completes.
| Compound | VIP |
|---|---|
| Research category | Sleep Cognitive |
| Available formats | 10mg*10vials |
| Starting price | From $430 USD per kit |
| Purity | Published on the lab-results page as verification completes |
| Test method | HPLC / ESI-MS |
| Certificate of analysis | Published online, matched to the vial lot number |
| Intended use | Laboratory research use only. Not for human consumption. |
| Handling | Supplied lyophilized, store per the stability guide |
Dr. Sudhir Menon
New Zealand
"Excellent neuropeptide for our brain research. High purity and reliable bioactivity."
2025-11-14
Prof. Christopher Wright
United States
"Premium quality VIP for our circadian studies. Consistent results across batches."
2025-11-11
Dr. Ingrid Svensson
Sweden
"High-quality peptide for our immunology research. Excellent documentation."
2025-11-07
About This Product
VIP (Vasoactive Intestinal Peptide) Research Guide
A 28 Amino Acid Neuropeptide With Broad Activity
Vasoactive Intestinal Peptide (VIP) is a 28 amino acid neuropeptide originally isolated from the gut, where it was characterized for its vasodilatory effects. Subsequent research has established VIP as a multifunctional signaling molecule acting across the nervous, immune, and gastrointestinal systems. It binds two main receptors (VPAC1 and VPAC2) that belong to the broader secretin receptor family of G-protein-coupled receptors.
VIP has one of the widest research profiles in the entire neuropeptide class, with documented effects spanning vasodilation, anti-inflammatory signaling, circadian rhythm modulation, neuroprotection, and gastrointestinal motility.
Mechanism
- VPAC1 and VPAC2 receptor activation: both receptors signal primarily through cAMP, with tissue-specific differences in downstream effects
- Anti-inflammatory signaling: shifts immune cell cytokine production toward a regulatory phenotype, with effects on T helper cell balance
- Circadian biology: VIP is a central signal in the suprachiasmatic nucleus, the master circadian pacemaker
- Neuroprotection: reduces excitotoxicity and supports neuronal survival in research stress models
- Vasodilation and smooth muscle relaxation: the original characterized effect from the gut isolation research
Research Applications
- Anti-inflammatory and immune modulation research
- Circadian biology and suprachiasmatic nucleus research
- Neuroprotection research in stroke and stress models
- Gastrointestinal motility and vasodilation research
- Comparative research against other neuropeptides with overlapping anti-inflammatory or neuroprotective effects
Quality Standards
- Analytical status: currently undergoing independent third-party analysis (Janoshik Analytical); the Certificate of Analysis is published at /lab-results once verification completes
- Form: lyophilized powder in sterile vials
- Storage: refrigerated for near-term use, minus 20 degrees Celsius for long-term storage
For research purposes only. Not for human consumption or therapeutic use.
Research Context for VIP
Sleep and Cognitive Research Context
Neuropeptides in this category are studied across circadian biology, memory consolidation, neuroprotection, and anxiolytic or nootropic pathways. Research models range from sleep architecture mapping in animal studies to behavioral learning paradigms and neurotransmitter-specific biomarker panels.
VIP ships as a lyophilized research reagent through the LyzeLabs™ catalog in the Sleep Cognitive category, available as a single research-grade format. Verified LyzeLabs compounds publish their full HPLC chromatogram and mass spectrometry confirmation, matched to the lot number on the vial, on the LyzeLabs lab results page; this compound's analytical data is published there as it completes verification.
Related Research Guides
Frequently Asked Questions
VIP
$430