B12
Premium vitamin B12 injectable solution for metabolic and energy research applications
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Lab-Grade Guarantee
If an independent HPLC assay of your lot comes back below the purity stated on our published Certificate of Analysis, we reship your order free. Verifiable, not a promise.
99.55% Purity Verified
HPLC (UV 361 nm) / ESI-MS Tested
FOR RESEARCH PURPOSES ONLY. This product is strictly for laboratory and research use. Not for human consumption, medical treatment, or any clinical application. By ordering, you confirm you are a qualified researcher or represent a legitimate research institution.
B12: Key Facts
B12 is a weight loss research peptide supplied by LyzeLabs as a lyophilized reference standard, strictly for laboratory research use. It is available in 1 format starting at $265 per kit. Each batch is independently HPLC-verified at 99.55% purity by Janoshik Analytical, with the certificate of analysis published on the lab-results page and matched to the lot number printed on the vial.
| Compound | B12 |
|---|---|
| Research category | Weight Loss |
| Available formats | 10ml*10vials |
| Starting price | From $265 USD per kit |
| Purity | 99.55% verified (third-party HPLC, Janoshik) |
| Test method | HPLC (UV 361 nm) / ESI-MS |
| Certificate of analysis | Published online, matched to the vial lot number |
| Intended use | Laboratory research use only. Not for human consumption. |
| Handling | Supplied lyophilized, store per the stability guide |
Dr. Anil Patel
Singapore
"Excellent quality B12 for our metabolic research at our institutional research lab. Purity exceeds specifications and delivery worldwide was prompt."
2025-11-15
Prof. Sarah Johnson
United States
"Reliable pharmaceutical-grade B12 for our energy metabolism studies. Consistent quality across multiple orders."
2025-11-12
Dr. Hans Mueller
Germany
"High-quality B12 solution for our neurological research. Excellent documentation and packaging."
2025-11-08
About This Product
Vitamin B12: Cobalamin Biochemistry and Methylation Research
Two Enzymes, One Cofactor
Vitamin B12 is the cofactor for exactly two mammalian enzymes. Methionine synthase uses methylcobalamin to transfer a methyl group from 5-methyltetrahydrofolate to homocysteine, regenerating methionine and recycling the folate pool. Methylmalonyl-CoA mutase uses adenosylcobalamin to isomerize methylmalonyl-CoA to succinyl-CoA, feeding odd-chain fatty acid carbons into the TCA cycle. These two reactions connect B12 to methylation biology, one-carbon metabolism, and mitochondrial substrate supply.
Cyanocobalamin vs Methylcobalamin in Research
Cyanocobalamin is the stable, commercially dominant form used in standardized research protocols. It requires cellular conversion to methylcobalamin and adenosylcobalamin via a MMACHC-dependent pathway. Methylcobalamin is the biologically active methyl-donor form with direct activity in methionine synthase catalysis. Research comparing the two forms examines conversion efficiency, tissue distribution, and cobalamin form-specific effects on homocysteine and SAM/SAH ratios.
Research Applications
- One-carbon metabolism: SAM/SAH ratio modulation and methyl donor availability studies
- Homocysteine research: remethylation pathway kinetics and cardiovascular risk models
- Neurological studies: cobalamin deficiency neuropathy models and myelin synthesis research
- Metabolic flux: methylmalonyl-CoA mutase activity and propionate catabolism
- Epigenetics: cobalamin dependency of CpG methylation patterns
Formulation Notes
This B12 formulation is a sterile injectable solution at 1000mcg/ml. Sterile injectable format is specified in research protocols requiring controlled delivery and precise dosing. Oral forms introduce absorption variability through intrinsic factor dependency, making the injectable form preferred for pharmacokinetic studies.
Quality Standards
- Purity: >99% by HPLC
- Form: sterile injectable solution, 1000mcg/ml
- Storage: 2-8°C, protect from light
- Full COA at lyzelabs.com/lab-results
For research purposes only. Not for human consumption.
Research Context for B12
Metabolic and Weight Loss Research Context
This compound sits in the incretin and metabolic peptide class, where research focuses on appetite regulation, glucose handling, energy expenditure, and the complex signaling network that connects gut, pancreas, liver, and hypothalamus. Research protocols in this category typically involve dose escalation, tolerability mapping, and long-duration observation of metabolic endpoints.
B12 ships as a lyophilized research reagent through the LyzeLabs™ catalog in the Weight Loss category, available as a single research-grade format. Every batch is independently verified by Janoshik Analytical, with the full HPLC chromatogram and mass spectrometry confirmation published on the LyzeLabs lab results page and matched to the lot number printed on your vial.
Related Research Guides
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How to Reconstitute a Research Peptide
The nine-step procedure, common mistakes, and per-compound notes for clean reconstitution.
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Frequently Asked Questions
B12
$265