5-Amino-1MQ
NNMT inhibitor for fat metabolism and anti-obesity research applications
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If an independent HPLC assay of your lot comes back below the purity stated on our published Certificate of Analysis, we reship your order free. Verifiable, not a promise.
99.18% Purity Verified
HPLC Tested
FOR RESEARCH PURPOSES ONLY. This product is strictly for laboratory and research use. Not for human consumption, medical treatment, or any clinical application. By ordering, you confirm you are a qualified researcher or represent a legitimate research institution.
5-Amino-1MQ: Key Facts
5-Amino-1MQ is a fat loss research peptide supplied by LyzeLabs as a lyophilized reference standard, strictly for laboratory research use. It is available in 2 formats starting at $330 per kit. Each batch is independently HPLC-verified at 99.18% purity by Janoshik Analytical, with the certificate of analysis published on the lab-results page and matched to the lot number printed on the vial.
| Compound | 5-Amino-1MQ |
|---|---|
| Research category | Fat Loss |
| Available formats | 5mg*10vials, 50mg*10vials |
| Starting price | From $330 USD per kit |
| Purity | 99.18% verified (third-party HPLC, Janoshik) |
| Test method | HPLC |
| Certificate of analysis | Published online, matched to the vial lot number |
| Intended use | Laboratory research use only. Not for human consumption. |
| Handling | Supplied lyophilized, store per the stability guide |
Dr. Deepak Sharma
Sweden
"Excellent NNMT inhibitor for our obesity research. High purity and consistent effects."
2025-11-14
Prof. Amanda Collins
United States
"Premium quality 5-Amino-1MQ for our metabolic studies. Reliable results."
2025-11-11
Dr. Thomas Berg
Norway
"High-quality compound for our fat metabolism research. Excellent documentation."
2025-11-07
About This Product
5-Amino-1MQ Research Guide
A Selective NNMT Inhibitor
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small molecule research compound and a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in the methylation of nicotinamide using S-adenosylmethionine (SAM) as a methyl donor. NNMT is elevated in obesity and certain metabolic disease research models, where it contributes to depletion of both the NAD salvage pathway precursor (nicotinamide) and the methyl donor pool (SAM).
Inhibiting NNMT is a research approach to preserving both pools simultaneously, which has downstream effects on NAD+ bioavailability, sirtuin activity, and methylation-dependent cellular processes.
Mechanism
- NNMT enzymatic inhibition: selectively blocks the methylation of nicotinamide to N1-methylnicotinamide
- NAD salvage pathway preservation: keeps nicotinamide available for reentry into the NAD+ biosynthesis pathway
- Methyl donor preservation: reduces SAM consumption by the NNMT reaction
- Downstream effects on adipocyte biology: research models show effects on adipocyte metabolism when NNMT activity is blocked
Research Applications
- Obesity research involving NNMT pathway modulation
- NAD+ biology research complementing [NAD+ Buffered](/product/nad-buffered) protocols
- Methylation pathway research
- Adipocyte metabolism studies
- Sirtuin activity research via downstream NAD+ preservation
Quality Standards
- Purity: 99 percent plus verified by independent third-party HPLC (Janoshik Analytical)
- Form: lyophilized powder in sterile vials
- Storage: refrigerator for near-term use, minus 20 degrees Celsius long-term
- Documentation: batch-matched Certificate of Analysis published at /lab-results
For research purposes only. Not for human consumption or therapeutic use.
Research Context for 5-Amino-1MQ
Lipolysis and Fat Metabolism Research Context
Fat metabolism research peptides target lipolysis, mitochondrial fatty acid oxidation, brown adipose activation, or direct effects on adipocyte viability. Research protocols measure body composition, lipid panel markers, and tissue-specific fat mobilization under defined experimental conditions.
5-Amino-1MQ ships as a lyophilized research reagent through the LyzeLabs™ catalog in the Fat Loss category, with 2 variant options sized to different research protocols. Every batch is independently verified by Janoshik Analytical, with the full HPLC chromatogram and mass spectrometry confirmation published on the LyzeLabs lab results page and matched to the lot number printed on your vial.
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Frequently Asked Questions
5-Amino-1MQ
$330